Seven other women under the age of 50 in terminal or preterminal renal failure were admitted for dialysis in and They had all followed a slimming regimen in the same medical clinic.
Renal biopsy samples in eight of the nine cases showed extensive interstitial fibrosis without glomerular lesions. Two of the patients nature slimming seen for the first time in terminal renal failure and nature slimming started immediately on dialysis.
For the seven other women, the nephropathy was characterised by a rapid deterioration in renal function, with initial serum creatinine doubling within about 3 months.
The clinic had specialised in slimming treatments for the previous 15 years without any problems. In May,therapy was changed, with the introduction of two Chinese herbs Stephania tetrandra and Magnolia officinalis. Nature slimming June,three of twenty-five randomly selected women who had followed the same regimen during at least 3 months from had impaired renal function.
Chemical analysis of some brands of these Chinese herbs did not show nephrotoxic contaminants of fungal or plant origin ochratoxin or aristolochic acid or adulteration by diuretics or antiinflammatory drugs. However, the medicinal preparation of the capsules taken by patients had different alkaloid profiles from those expected in Chinese plants. The striking relation between a specific type of nature slimming interstitial nephritis in young women and a slimming treatment involving Chinese herbs adds support to the arguments against uncontrolled therapy with herbal preparations.